In 1993, the NIH Revitalization Act included language, supported by corporations and animal advocates, that authorized a new program to develop and validate toxicity tests that would replace and reduce the use of laboratory animals. Seven years later, that 1993 Act led to the passage of the 2000 ICCVAM Authorization Act. This act established the Interagency Coordinating Committee for the Validation of Alternative Methods (ICCVAM) to facilitate the development and implementation of alternative methods that would replace or reduce the use of animals in safety testing and risk assessment. ICCVAM started slowly, but twenty-one years after its formal launch, it is now delivering significant progress in replacing animal tests.
Rowan, Andrew N.
"Replacing Laboratory Animals in Safety Testing,"
WellBeing News: Vol. 3:
11, Article 2.
Available at: https://www.wellbeingintlstudiesrepository.org/wbn/vol3/iss11/2